Recombinant Human BLK, His-tagged
Cat.No. : | BLK-26112TH |
Product Overview : | Recombinant full length Human BLK with an N terminal His tag 59.8 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. |
Protein length : | 505 amino acids |
Conjugation : | HIS |
Molecular Weight : | 59.800kDa inclusive of tags |
Source : | Baculovirus infected High-5 cells |
Tissue specificity : | Expressed in lymphatic organs, pancreatic islets, Leydig cells, striate ducts of salivary glands and hair follicles. |
Form : | Liquid |
Purity : | by SDS-PAGE |
Storage buffer : | pH: 8.00Constituents:0.32% Tris HCl, 30% Glycerol, 0.58% Sodium chloride, 0.02% DTT, 0.002% PMSF |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHHSSGLVPRGSHMGLVS SKKPDKEKPIKEKDKGQWSPLKVSA QDKDAPPLPPLVVFNHLTPPPPDEH LDEDKHFVVALYDYTAMNDRDLQML KGEKLQVLKGTGDWWLARSLVTGRE GYVPSNFVARVESLEMERWFFRSQG RKEAERQLLAPINKAGSFLIRESET NKGAFSLSVKDVTTQGELIKHYKIR CLDEGGYYISPRITFPSLQALVQHY SKKGDGLCQRLTLPCVRPAPQNPWA QDEWEIPRQSLRLVRKLGSGQFGEV WMGYYKNNMKVAIKTLKEGTMSPEA FLGEANVMKALQHERLVRLYAVVTK EPIYIVTEYMARGCLLDFLKTDEGS RLSLPRLIDMSAQIAEGMAYIERMN SIHRDLRAANILVSEALCCKIADFG LARIIDSEYTAQEGAKFPIKWTAPE AIHFGVFTIKADVWSFGVLLMEVVT YGRVPYPGMSNPEVIRNLERGYRMP RPDTCPPELYRGVIAECWRSRPEER PTFEFLQSVLEDFYTATERQYELQP |
Sequence Similarities : | Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.Contains 1 protein kinase domain.Contains 1 SH2 domain.Contains 1 SH3 domain. |
Gene Name : | BLK B lymphoid tyrosine kinase [ Homo sapiens ] |
Official Symbol : | BLK |
Synonyms : | BLK; B lymphoid tyrosine kinase; tyrosine-protein kinase Blk; MGC10442; |
Gene ID : | 640 |
mRNA Refseq : | NM_001715 |
Protein Refseq : | NP_001706 |
MIM : | 191305 |
Uniprot ID : | P51451 |
Chromosome Location : | 8p23-p22 |
Pathway : | Alpha-synuclein signaling, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Class I PI3K signaling events, organism-specific biosystem; EPHA forward signaling, organism-specific biosystem; |
Function : | ATP binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein tyrosine kinase activity; |
Products Types
◆ Recombinant Protein | ||
BLK-0746H | Recombinant Human BLK Protein (G2-P505), GST tagged | +Inquiry |
BLK-5368H | Recombinant Human B Lymphoid Tyrosine Kinase, His-tagged | +Inquiry |
BLK-1039M | Recombinant Mouse BLK Protein, His (Fc)-Avi-tagged | +Inquiry |
BLK-01H | Recombinant Human BLK Protein, His-tagged | +Inquiry |
BLK-0745H | Recombinant Human BLK Protein (G2-P505), Tag Free | +Inquiry |
◆ Lysates | ||
BLK-614HCL | Recombinant Human BLK cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1565 | BLK Kinase Binding Assay Kit | +Inquiry |
Kit-1566 | BLK Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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