Recombinant Mouse Myosin, Light Polypeptide 9, Regulatory, GST-tagged

• Cat.No.: Myl9-1468M
• Product Overview: Recombinant full-length mouse LC20 was expressed inE. colicells using an N-terminal GST tag. MW = 45kDa.

Specification

• Cat. No.: Myl9-1468M
• Description: LC20 is the myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. LC20 protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for LC20 and the deduced 172-amino acid protein is highly conserved, with only 3 differences between the human and chicken proteins. Light chain phosphorylation causes the folded monomeric form of myosin to extend and assemble into filaments. This observation established the involvement of the LC20 in conformational transitions of smooth muscle myosin.
• Source: E. coli.
• Sequence: Full-length.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: Myl9 myosin, light polypeptide 9, regulatory [ Mus musculus ]
• Synonyms: Myl9; myosin, light polypeptide 9, regulatory; MLC20; RLC-C; Mylc2c; AI327049
• Gene ID: 98932
• mRNA Refseq: NM_172118
• Protein Refseq: NP_742116
• UniProt ID: Q9CQ19
• Chromosome Location: 2
• Pathway: Focal adhesion; Leukocyte transendothelial migration; Regulation of actin cytoskeleton; Tight junction; Vascular smooth muscle contraction
• Function: calcium ion binding; motor activity