Recombinant Human CAMK4

• Cat.No.: CAMK4-26208TH
• Product Overview: Recombinant full length CAMKIV protein (Human), expressed by baculovirus in Sf9 insect cells using a N-terminal tag, MW 79kDa.

Specification

• Description: The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.
• Tissue specificity: Expressed in epithelial ovarian cancer tissue.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.Contains 1 protein kinase domain.

Gene Information

• Gene Name: CAMK4 calcium/calmodulin-dependent protein kinase IV [ Homo sapiens ]
• Official Symbol: CAMK4
• Synonyms: CAMK4; calcium/calmodulin-dependent protein kinase IV; calcium/calmodulin-dependent protein kinase type IV; brain Ca++ calmodulin dependent protein kinase type IV; calcium/calmodulin dependent protein kinase type IV catalytic chain; CAM kinase IV; CAM kin
• Gene ID: 814
• mRNA Refseq: NM_001744
• Protein Refseq: NP_001735
• MIM: 114080
• Uniprot ID: Q16566
• Chromosome Location: 5q21-q23
• Pathway: Activation of CaMK IV, organism-specific biosystem; Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; CREB phosphorylation through the activation of CaMKK, organism-specific biosystem; Ca-dependent events, organism-specific biosystem; CaM pathway, organism-specific biosystem
• Function: ATP binding; calmodulin binding; calmodulin-dependent protein kinase activity; nucleotide binding