Recombinant Human CCL17, His-tagged

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Recombinant Human CCL17, His-tagged

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Cat.No. : CCL17-30149TH
Product Overview : Full-length soluble Human, His-tagged, Recombinant CCL17, MW 10.3kDA.
Description : This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.
Conjugation : HIS
Source : E. coli
Tissue specificity : Expressed at high levels in thymus and at low levels in the lung, colon and small intestine.
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 10% Glycerol, PBS, pH 7.4
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MARGTNVGRE CCLEYFKGAI PLRKLKTWYQ TSEDCSRDAI VFVTVQGRAI CSDPNNKRVK NAVKYLQSLE RS
Sequence Similarities : Belongs to the intercrine beta (chemokine CC) family.
Gene Name : CCL17 chemokine (C-C motif) ligand 17 [ Homo sapiens ]
Official Symbol : CCL17
Synonyms : CCL17; chemokine (C-C motif) ligand 17; SCYA17, small inducible cytokine subfamily A (Cys Cys), member 17; C-C motif chemokine 17; ABCD 2; TARC;
Gene ID : 6361
mRNA Refseq : NM_002987
Protein Refseq : NP_002978
MIM : 601520
Uniprot ID : Q92583
Chromosome Location : 16q13
Pathway : Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem;
Function : chemokine activity; receptor binding;

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