Recombinant Human HIV-1 Tat Interactive Protein 2, 30kDa, His-tagged
Cat.No. : | HTATIP2-2723H |
Product Overview : | Recombinant humanHTATIP2 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 29.3 kDa (262aa),confirmed by MALDI-TOF. |
- Specification
- Gene Information
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Cat. No. : | HTATIP2-2723H |
Description : | HTATIP2, also known as TIP30, is a member of the short-chain dehydrogenases/reductases (SDR) family. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in This protein are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for HTATIP2 in antitumor therapy. |
Source : | E.coli. |
Sequences Of Amino Acids : | MGSSHHHHHH SSGLVPRGSH MAETEALSKL REDFRMQNKS VFILGASGET GRVLLKEILE QGLFSKVTLI GRRKLTFDEE AYKNVNQEVV DFEKLDDYAS AFQGHDVGFC CLGTTRGKAG AEGFVRVDRD YVLKSAELAK AGGCKHFNLL SSKGADKSSN FLYLQVKGEV EAKVEELKFD RYSVFRPGVL LCDRQESRPG EWLVRKFFGS LPDSWARGHS VPVVTVVRAM LNNVVRPRDK QMELLENKAI HDLGKAHGSL KP |
Form : | Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT. |
Purity : | > 95% by SDS – PAGE. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | HTATIP2 HIV-1 Tat interactive protein 2, 30kDa [ Homo sapiens ] |
Synonyms : | HTATIP2; HIV-1 Tat interactive protein 2, 30kDa; oxidoreductase HTATIP2; Tat-interacting protein (30kD); HIV-1 TAT-interactive protein 2; 30 kDa HIV-1 TAT-interacting protein; short chain dehydrogenase/reductase family 44U, member 1; EC 1.1.1.-; CC3; TIP30; SDR44U1; FLJ26963 |
Gene ID : | 10553 |
mRNA Refseq : | NM_001098520 |
Protein Refseq : | NP_001091990 |
MIM : | 605628 |
UniProt ID : | Q9BUP3 |
Chromosome Location : | 11p15.1 |
Function : | NAD or NADH binding; RNA polymerase II transcription factor activity; oxidoreductase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; protein binding; transcription coactivator activity |
Products Types
◆ Recombinant Protein | ||
HTATIP2-4371M | Recombinant Mouse HTATIP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
HTATIP2-2193H | Recombinant Human HTATIP2 Protein, MYC/DDK-tagged | +Inquiry |
HTATIP2-5256H | Recombinant Human HTATIP2 Protein, GST-tagged | +Inquiry |
Htatip2-3461M | Recombinant Mouse Htatip2 Protein, Myc/DDK-tagged | +Inquiry |
HTATIP2-7927M | Recombinant Mouse HTATIP2 Protein | +Inquiry |
◆ Lysates | ||
HTATIP2-826HCL | Recombinant Human HTATIP2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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