Recombinant Human CDK2AP1, His-tagged
Cat.No. : | CDK2AP1-27910TH |
Product Overview : | Recombinant full length Human CDKA1 / DOC1 with a N terminal His tag. 152 amino acids with a predicted MWt 16.6 kDa including tag. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes. |
Protein length : | 115 amino acids |
Conjugation : | HIS |
Molecular Weight : | 16.600kDa inclusive of tags |
Source : | E. coli |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | pH: 8.00Constituents:0.32% Tris HCl, 0.58% Sodium chloride, 20% Glycerol |
Storage : | Please see Notes section |
Sequences of amino acids : | RGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSY KPNLAAHMPA AALNAAGSVH SPSTSMATSS QYRQLLSDYG PPSLGYTQGT GNSQVPQSKY AELLAIIEEL GKEIRPTYAG SKSAMERLKR GIIHARGLVR ECLAETERNA RS |
Sequence Similarities : | Belongs to the CDK2AP family. |
Gene Name : | CDK2AP1 cyclin-dependent kinase 2 associated protein 1 [ Homo sapiens ] |
Official Symbol : | CDK2AP1 |
Synonyms : | CDK2AP1; cyclin-dependent kinase 2 associated protein 1; CDK2 associated protein 1; cyclin-dependent kinase 2-associated protein 1; doc 1; DOC1; DORC1; p12DOC 1; ST19; |
Gene ID : | 8099 |
mRNA Refseq : | NM_004642 |
Protein Refseq : | NP_004633 |
MIM : | 602198 |
Uniprot ID : | O14519 |
Chromosome Location : | 12q24 |
Function : | DNA binding; |
Products Types
◆ Recombinant Protein | ||
CDK2AP1-1523M | Recombinant Mouse CDK2AP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Cdk2ap1-2088M | Recombinant Mouse Cdk2ap1 Protein, Myc/DDK-tagged | +Inquiry |
CDK2AP1-1005H | Recombinant Human CDK2AP1 Protein, GST-Tagged | +Inquiry |
CDK2AP1-11047H | Recombinant Human CDK2AP1, GST-tagged | +Inquiry |
CDK2AP1-27911TH | Recombinant Human CDK2AP1, His-tagged | +Inquiry |
◆ Lysates | ||
CDK2AP1-7628HCL | Recombinant Human CDK2AP1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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