"CDK2AP1" Related Products

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Recombinant Human CDK2AP1, His-tagged

Cat.No.: CDK2AP1-27910TH
Product Overview: Recombinant full length Human CDKA1 / DOC1 with a N terminal His tag. 152 amino acids with a predicted MWt 16.6 kDa including tag.
Description: The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes.
Protein length: 115 amino acids
Conjugation: HIS
Molecular Weight: 16.600kDa inclusive of tags
Source: E. coli
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 0.58% Sodium chloride, 20% Glycerol
Storage: Please see Notes section
Sequences of amino acids: RGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSY KPNLAAHMPA AALNAAGSVH SPSTSMATSS QYRQLLSDYG PPSLGYTQGT GNSQVPQSKY AELLAIIEEL GKEIRPTYAG SKSAMERLKR GIIHARGLVR ECLAETERNA RS
Sequence Similarities: Belongs to the CDK2AP family.
Gene Name: CDK2AP1 cyclin-dependent kinase 2 associated protein 1 [ Homo sapiens ]
Official Symbol: CDK2AP1
Synonyms: CDK2AP1; cyclin-dependent kinase 2 associated protein 1; CDK2 associated protein 1; cyclin-dependent kinase 2-associated protein 1; doc 1; DOC1; DORC1; p12DOC 1; ST19;
Gene ID: 8099
mRNA Refseq: NM_004642
Protein Refseq: NP_004633
MIM: 602198
Uniprot ID: O14519
Chromosome Location: 12q24
Function: DNA binding;

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