Recombinant Human CHKA

• Cat.No.: CHKA-26903TH
• Product Overview: Recombinant full length Human Choline kinase alpha protein with an N terminal proprietary tag; predicted mwt: 76.34 kDa inclusive of tag.

Specification

• Description: The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene.
• Protein length: 457 amino acids
• Molecular Weight: 76.340kDa inclusive of tags
• Source: Wheat germ
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MKTKFCTGGEAEPSPLGLLLSCGSGSAAPAPGVGQQRDAA SDLESKQLGGQQPPLALPPPPPLPLPLPLPQPPPPQPPAD EQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGL SNMLFQCSLPDTTATLGDEPRKVLLRLYGAILQMRSCNKE GSEQAQKENEFQGAEAMVLESVMFAILAERSLGPKLYGIF PQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKM PFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSY NLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGREN SEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYP FFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSI IKEEMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMDY AQARFDAYFHQKRKLGV

Gene Information

• Gene Name: CHKA choline kinase alpha [ Homo sapiens ]
• Official Symbol: CHKA
• Synonyms: CHKA; choline kinase alpha; CHK, choline kinase; CKI
• Gene ID: 1119
• mRNA Refseq: NM_001277
• Protein Refseq: NP_001268
• MIM: 118491
• Uniprot ID: P35790
• Chromosome Location: 11q13.1
• Pathway: Acetylcholine Synthesis, organism-specific biosystem; Glycerophospholipid metabolism, organism-specific biosystem; Glycerophospholipid metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Phosphatidylcholine (PC) biosynthesis, choline =>
• Function: ATP binding; choline binding; choline kinase activity; drug binding; ethanolamine kinase activity