"CHML" Related Products

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Recombinant Human CHML, His-tagged

Cat.No.: CHML-26718TH
Product Overview: Recombinant full length Human CHML expressed in Saccharomyces cerevisiae with His tag; amino acids 1-656, Predicted MWt 74kDa.
Description: The product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP-1 in tissues other than retina. CHML is localized close to the gene for Usher syndrome type II.
Conjugation: HIS
Biological activity: Activity:1 pmol of CHML will mediate transfer of 2 pmol of geranylgeraniol by RabGGTase onto 1 pmol of Rab7 in 3 minutes.
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 5mM DTT, 40mM Sodium chloride, 25mM HEPES, pH 7.2
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Gene Name: CHML choroideremia-like (Rab escort protein 2) [ Homo sapiens ]
Official Symbol: CHML
Synonyms: CHML; choroideremia-like (Rab escort protein 2); rab proteins geranylgeranyltransferase component A 2; REP 2;
Gene ID: 1122
mRNA Refseq: NM_001821
Protein Refseq: NP_001812
MIM: 118825
Uniprot ID: P26374
Chromosome Location: 1q42-qter
Function: GTPase activator activity; Rab geranylgeranyltransferase activity;

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