||Recombinant fragment, corresponding to amino acids 746-1011 of Human CYLN2 with N terminal His tag, Predicted MWt 31 kDa.
||The protein encoded by this gene belongs to the family of cytoplasmic linker proteins, which have been proposed to mediate the interaction between specific membranous organelles and microtubules. This protein was found to associate with both microtubules and an organelle called the dendritic lamellar body. This gene is hemizygously deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.
||Lyophilised:Reconstitute with 56 μl aqua dest.
||Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
||Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
|Sequences of amino acids:
||ESLREKLLVAENRLQAVEALCSSQHTHMIESNDISEETIR TKETVEGLQDKLNKRDKEVTALTSQTEMLRAQVSALES KCKSGEKKVDALLKEKRRLEAELETVSRKTHDASGQLV LISQELLRKERSLNELRVLLLEANRHSPGPERDLSREV HKAEWRIKEQKLKDDIRGLREKLTGLDKEKSLSDQRRYSLIDPSSAPELLRLQHQLMSTEDALRDALDQAQQVEKLME AMRSCPDKAQTIGNSGSANGIHQQDKAQKQEDKH
||Contains 2 CAP-Gly domains.