||Recombinant human CCNI (aa. 1-377) produced inE.coliis a 43.4 kDa protein. It was fused to T7 tag at N-terminus.
||This protein belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of the gene was found to be expressed constantly during cell cycle progression. The function of this cyclin has not yet been determined.
||E, WB, MS.
||10 mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3, 10mM DTT.
||Store at -70°C with any protein, exposing CCNI recombinant protein to repeated freeze/thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.