Recombinant Human CRMP1

• Cat.No.: CRMP1-26625TH
• Product Overview: Recombinant fusion protein with N terminal tag, corresponding to amino acids 448-568 of Human CRMP1

Specification

• Description: This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Tissue specificity: Brain.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.

Gene Information

• Gene Name: CRMP1 collapsin response mediator protein 1 [ Homo sapiens ]
• Official Symbol: CRMP1
• Synonyms: CRMP1; collapsin response mediator protein 1; dihydropyrimidinase-related protein 1; DPYSL1; DRP 1
• Gene ID: 1400
• mRNA Refseq: NM_001014809
• Protein Refseq: NP_001014809
• MIM: 602462
• Uniprot ID: Q14194
• Chromosome Location: 4p16.1
• Pathway: Axon guidance, organism-specific biosystem; CRMPs in Sema3A signaling, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Semaphorin interactions, organism-specific biosystem
• Function: dihydropyrimidinase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides; protein binding