Recombinant Human CRP

• Cat.No.: CRP-26069TH
• Product Overview: Recombinant full length mature Human C Reactive Protein ; 207 amino acids with the tag; predicted MWt: 23.2 kDa.

Specification

• Description: The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli.
• Protein length: 226 amino acids
• Molecular Weight: 23.200kDa inclusive of tags
• Source: E. coli
• Tissue specificity: Found in plasma.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:20% Glycerol, 12.01% UreaNote: Contains 67% Tris-HCl buffer.
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MQTDMSRKAFVFPKESDTSYVSLKA PLTKPLKAFTVCLHFYTELSSTRGY SIFSYATKRQDNEILIFWSKDIGYS FTVGGSEILFEVPEVTVAPVHICTS WESASGIVEFWVDGKPRVRKSLKKG YTVGAEASIILGQEQDSFGGNFEGS QSLVGDIGNVNMWDFVLSPDEINTI YLGGPFSPNVLNWRALKYEVQGEVF TKPQLWP
• Sequence Similarities: Belongs to the pentaxin family.Contains 1 pentaxin domain.

Gene Information

• Gene Name: CRP C-reactive protein, pentraxin-related [ Homo sapiens ]
• Official Symbol: CRP
• Synonyms: CRP; C-reactive protein, pentraxin-related; C-reactive protein; pentraxin 1; PTX1
• Gene ID: 1401
• mRNA Refseq: NM_000567
• Protein Refseq: NP_000558
• MIM: 123260
• Uniprot ID: P02741
• Chromosome Location: 1q21-q23
• Pathway: Classical antibody-mediated complement activation, organism-specific biosystem; Complement cascade, organism-specific biosystem; Creation of C4 and C2 activators, organism-specific biosystem; IL6-mediated signaling events, organism-specific biosystem; Immune System, organism-specific biosystem
• Function: Gram-positive bacterial cell surface binding; binding; cholesterol binding; choline binding; low-density lipoprotein particle binding