Recombinant Human CSDE1, His-tagged

• Cat.No.: CSDE1-28019TH
• Product Overview: Recombinant fragment, corresponding to amino acids 515-767 of Human CSDE1 Isoform 2 with N terminal His tag; Predicted MWt 29 kDa.

Specification

• Description: RNA-binding protein. Required for internal initiation of translation of human rhinovirus RNA. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 132 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: YSEFSGDVDSLELGDMVEYSLSKGKGNKVSAEKVNKTHSV NGITEEADPTIYSGKVIRPLRSVDPTQTEYQGMIEIVE EGDMKGEVYPFGIVGMANKGDCLQKGESVKFQLCVLGQ NAQTMAYNITPLRRATVECVKDQFGFINYEVGDSKKLF FHVKEVQDGIELQAGDEVEFSVILNQRTGKCSACNVWRVC EGPKAVAAPRPDRLVNRLKNITLDDASAPRLMVLRQPR GPDNSMGFGAERKIRQAGVID

Gene Information

• Gene Name: CSDE1 cold shock domain containing E1, RNA-binding [ Homo sapiens ]
• Official Symbol: CSDE1
• Synonyms: CSDE1; cold shock domain containing E1, RNA-binding; cold shock domain-containing protein E1; D1S155E; UNR; upstream of NRAS
• Gene ID: 7812
• mRNA Refseq: NM_001130523
• Protein Refseq: NP_001123995
• MIM: 191510
• Uniprot ID: O75534
• Chromosome Location: 1p13.2
• Pathway: Validated targets of C-MYC transcriptional repression, organism-specific biosystem
• Function: DNA binding; RNA binding