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Recombinant Human CSNK1E

Cat.No. : CSNK1E-27754TH
Product Overview : Full length recombinant Human CK1 epsilon with N-terminal proprietary tag, 72kDa.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene.
Protein length : 416 amino acids
Molecular Weight : 72.000kDa inclusive of tags
Source : Baculovirus infected sf9 cells
Tissue specificity : Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. Expressed in monocytes and lymphocytes but not in granulocytes.
Biological activity : The Specific activity of CSNK1E-27754TH was determined to be 46 nmol/min/mg.
Form : Liquid
Purity : by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.Contains 1 protein kinase domain.
Gene Name : CSNK1E casein kinase 1, epsilon [ Homo sapiens ]
Official Symbol : CSNK1E
Synonyms : CSNK1E; casein kinase 1, epsilon; casein kinase I isoform epsilon; HCKIE;
Gene ID : 1454
mRNA Refseq : NM_001894
Protein Refseq : NP_001885
MIM : 600863
Uniprot ID : P49674
Chromosome Location : 22q13.1
Pathway : Canonical Wnt signaling pathway, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Centrosome maturation, organism-specific biosystem; Circadian Clock, organism-specific biosystem; Circadian rhythm - mammal, organism-specific biosystem;
Function : ATP binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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