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Recombinant Human CSNK2A1

Cat.No.: CSNK2A1-28001TH
Product Overview: Recombinant full length CKII alpha protein (Human), was expressed by baculovirus in Sf9 insect cells using a N-terminal tag, MW 70kDa.
Description: Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene.
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.Contains 1 protein kinase domain.
Gene Name: CSNK2A1 casein kinase 2, alpha 1 polypeptide [ Homo sapiens ]
Official Symbol: CSNK2A1
Synonyms: CSNK2A1; casein kinase 2, alpha 1 polypeptide; casein kinase II subunit alpha;
Gene ID: 1457
mRNA Refseq: NM_001895
Protein Refseq: NP_001886
MIM: 115440
Uniprot ID: P68400
Chromosome Location: 20p13
Pathway: Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Alpha-synuclein signaling, organism-specific biosystem; Axon guidance, organism-specific biosystem; BCR signaling pathway, organism-specific biosystem;
Function: ATP binding; beta-catenin binding; nucleotide binding; protein N-terminus binding; protein binding;

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