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Recombinant Human CTHRC1 protein, GST-tagged

Cat.No. : CTHRC1-28025TH
Product Overview : Recombinant Human CTHRC1(32 a.a. - 141 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.
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  • Gene Information
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Description : This locus encodes a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcript variants have been described.
Source : Wheat Germ
Species : Human
Tag : GST
Form : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass : 37.62 kDa
AA Sequence : EIPKGKQKAQLRQREVVDLYNGMCL QGPAGVPGRDGSPGANGIPGTPGIP GRDGFKGEKGECLRESFEESWTPNY KQCSWSSLNYGIDLGKIAECTFTKM RSNSALRVLF
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name : CTHRC1 collagen triple helix repeat containing 1 [ Homo sapiens ]
Official Symbol : CTHRC1
Synonyms : CTHRC1; collagen triple helix repeat containing 1; collagen triple helix repeat-containing protein 1;
Gene ID : 115908
mRNA Refseq : NM_001256099
Protein Refseq : NP_001243028
MIM : 610635
UniProt ID : Q96CG8
Chromosome Location : 8q22.3
Pathway : Noncanonical Wnt signaling pathway, organism-specific biosystem; Wnt signaling network, organism-specific biosystem;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What factors regulate the expression and activity of CTHRC1 protein? 06/07/2023

Environmental factors, inflammatory responses, and mechanical stress can regulate the expression and activity of CTHRC1.

What role does CTHRC1 protein play in tissue repair and remodeling? 01/16/2021

CTHRC1 promotes cell migration and downregulates collagen synthesis in tissue repair, aiding in tissue remodeling.

How do structural changes in CTHRC1 protein affect its biological function? 01/11/2021

Structural changes in CTHRC1 may affect its interactions with the extracellular matrix and other proteins, altering its function.

How does the interaction of CTHRC1 protein with the Wnt signaling pathway affect cell proliferation and differentiation? 06/28/2020

The interaction of CTHRC1 with the Wnt signaling pathway influences cell proliferation and differentiation, especially in cancer and tissue repair.

What is the role of CTHRC1 protein in cardiovascular diseases? 04/01/2019

In cardiovascular diseases, CTHRC1 is involved in the remodeling and repair of blood vessels.

How does CTHRC1 protein affect the invasiveness and metastasis of cancer cells? 11/10/2018

CTHRC1 enhances cancer cell invasiveness and metastatic potential by facilitating extracellular matrix remodeling and signal transduction.

How does the expression level of CTHRC1 protein vary in different types of cancer? 07/11/2017

CTHRC1 expression is often increased in various cancers, associated with aggressiveness and severity of the disease.

Customer Reviews (3)

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Reviews
02/19/2023

    Consistent quality, a go-to for researchers.

    11/24/2018

      Expertise and professionalism in every analysis.

      06/22/2017

        Reliable support for our protein studies.

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