Recombinant Human CTPS, His-tagged

• Cat.No.: CTPS-28031TH
• Product Overview: Recombinant fragment, corresponding to amino acids 322-591 of Human CTP synthase with N terminal His tag; MWt ~36 kDa,

Specification

• Description: The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis.
• Protein length: 269 amino acids
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitution with 89 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: (Amino acid sequence (Sequence determined by 5 Sequencing))EHSALAINHKLEIKYIDSADLEPITS QEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAI AWARNQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFD PTTSHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKNSV MRKLYGDADYLEERHRHRFEVNPVWKKCLEEQGLKFVG QDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYF GLLLASVGRLSHYLQKGCRLSPRDTYSDRSGSSSPDSE ITELKFPSINHD

Gene Information

• Gene Name: CTPS CTP synthase [ Homo sapiens ]
• Official Symbol: CTPS
• Synonyms: CTPS; CTP synthase; CTP synthase 1
• Gene ID: 1503
• mRNA Refseq: NM_001905
• Protein Refseq: NP_001896
• MIM: 123860
• Uniprot ID: P17812
• Chromosome Location: 1p34.1
• Pathway: Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Pyrimidine metabolism, organism-specific biosystem; Pyrimidine metabolism, conserved biosystem
• Function: ATP binding; CTP synthase activity; CTP synthase activity; CTP synthase activity; ligase activity