Native Human CTRC

• Cat.No.: CTRC-27191TH
• Product Overview: Full length Human Chymotrypsin purified from Human Pancreas; amino acids 30-268, MWt 25kDa.

Specification

• Description: This gene encodes a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
• Tissue specificity: Pancreas.
• Biological activity: Activity: 40-70 units per mg protein. One unit is defined as the amount of enzyme that hydrolyzes one µmole of Suc-Ala-Ala-Pro-Phe-pNA per minute at 25°C, pH 8.0
• Form: Lyophilised
• Purity: >95% by SDS-PAGE
• Storage buffer: Buffer is 2 mM HCl
• Storage: Shipped at 4°C. Store at -20oC.
• Sequence Similarities: Belongs to the peptidase S1 family. Elastase subfamily.Contains 1 peptidase S1 domain.

Gene Information

• Gene Name: CTRC chymotrypsin C (caldecrin) [ Homo sapiens ]
• Official Symbol: CTRC
• Synonyms: CTRC; chymotrypsin C (caldecrin); chymotrypsin-C; CLCR; ELA4; elastase 4
• Gene ID: 11330
• mRNA Refseq: NM_007272
• Protein Refseq: NP_009203
• MIM: 601405
• Uniprot ID: Q99895
• Chromosome Location: 1p36.21
• Function: peptidase activity; serine-type endopeptidase activity