"CXCR3" Related Products

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Recombinant Human CXCR3, GST-tagged

Cat.No.: CXCR3-28064TH
Product Overview: Recombinant Human CXCR3(121 a.a. - 220 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ.
Description: This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4.
Source: Wheat germ
Species: Human
Tag: GST
Molecular Mass: 36.74 kDa
AA Sequence: SGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPARVTLTCLAVWGLCLLFALPDFIFLSAHHD ERLNATHCQYNFPQVGRTALRVLQL
Applications: ELISA; WB-Re; AP; Array
Notes: Best use within three months from the date of receipt of this protein.
Storage: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name: CXCR3 chemokine (C-X-C motif) receptor 3 [ Homo sapiens (human) ]
Official Symbol: CXCR3
Synonyms: CXCR3; chemokine (C-X-C motif) receptor 3; G protein coupled receptor 9 , GPR9; C-X-C chemokine receptor type 3; CD183; CKR L2; CMKAR3; IP10 R; MigR
Gene ID: 2833
mRNA Refseq: NM_001142797
Protein Refseq: NP_001136269
MIM: 300574
UniProt ID: P49682
Chromosome Location: Xq13
Pathway: Chemokine receptors bind chemokines; Chemokine signaling pathway; Cytokine-cytokine receptor interaction
Function: C-X-C chemokine binding; C-X-C chemokine receptor activity; chemokine receptor activity

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