||Recombinant fragment, corresponding to amino acids 289-467 of Human Drebrin with N terminal His tag; 179 amino acids, 20.6kDa.
||The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimers disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
||Lyophilised:Reconstitute with 134 μl aqua dest.
||Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
||Store at 4°C. Upon reconstitution store at -80oC.
|Sequences of amino acids:
||NPREFFKQQERVASASAGSCDVPSPFNHRPGSHLDSHRRM APTPIPTRSPSDSSTASTPVAEQIERALDEVTSSQPPP LPPPPPPAQETQEPSPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEPATADAT EIHDAADTIETDTATADTTVANN