Recombinant Human DNAJB2, His-tagged

• Cat.No.: DNAJB2-26154TH
• Product Overview: Recombinant full length Human DNAJB2 isoform 2 with a N terminal His tag; total protein length is 300 aa inclusive of tag; predicted molecular weight 33 kDa.

Specification

• Description: This gene is almost exclusively expressed in the brain, mainly in the neuronal layers. It encodes a protein that shows sequence similarity to bacterial DnaJ protein and the yeast homologs. In bacteria, this protein is implicated in protein folding and protein complex dissociation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Protein length: 277 amino acids
• Conjugation: HIS
• Molecular Weight: 33.000kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: 0% NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMGSMA SYYEILDVPRSASADDIKKAYRRKA LQWHPDKNPDNKEFAEKKFKEVAEA YEVLSDKHKREIYDRYGREGLTGTG TGPSRAEAGSGGPGFTFTFRSPEEV FREFFGSGDPFAELDDLGPFSELQN RGSRHSGPFFTFSSSFPGHSDFSSS SFSFSPGAGAFRSSTSTTFVQGRRI TTRRIMENGQERVEVEEDGQLKSVT INGVPDDLALGLELSRREQQPSVTS RSGGTQVQQTPASCPLDSDLSEDED LQLAMAYSLSEMEAAGKKPADVF

Gene Information

• Gene Name: DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 [ Homo sapiens ]
• Official Symbol: DNAJB2
• Synonyms: DNAJB2; DnaJ (Hsp40) homolog, subfamily B, member 2; HSJ1; dnaJ homolog subfamily B member 2; HSPF3
• Gene ID: 3300
• mRNA Refseq: NM_001039550
• Protein Refseq: NP_001034639
• MIM: 604139
• Uniprot ID: P25686
• Chromosome Location: 2q32-q34
• Pathway: Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem
• Function: Hsp70 protein binding; heat shock protein binding; polyubiquitin binding; proteasome binding; protein binding