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Recombinant Human DNAJB6, His-tagged

Cat.No.: DNAJB6-26155TH
Product Overview: Recombinant full length Human DNAJB6 with an N terminal His tag; 349 amino acids with the tag, predicted mwt: 38.5 kDa.
Description: This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the J-domain and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.
Protein length: 326 amino acids
Conjugation: HIS
Molecular Weight: 38.500kDa inclusive of tags
Source: E. coli
Tissue specificity: Widely expressed. Highest levels in testis and brain, and lower levels in heart, spleen, intestine, ovary, placenta, lung, kidney, pancreas, thymus, prostate, skeletal muscle, liver and leukocytes. In testis, expressed in germ cells in the earlier stages
Form: Liquid
Purity: by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 30% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, pH 8.0
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: DNAJB6-26155TH is purified using conventional chromatography techniques.
Sequence Similarities: Contains 1 J domain.
Gene Name: DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 [ Homo sapiens ]
Official Symbol: DNAJB6
Synonyms: DNAJB6; DnaJ (Hsp40) homolog, subfamily B, member 6; dnaJ homolog subfamily B member 6; MRJ;
Gene ID: 10049
mRNA Refseq: NM_005494
Protein Refseq: NP_005485
MIM: 611332
Uniprot ID: O75190
Chromosome Location: 7q36.3
Function: ATPase activator activity; DNA binding; chaperone binding; heat shock protein binding; protein binding;

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