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Recombinant Human DPH2

Cat.No. : DPH2-28432TH
Product Overview : Recombinant full length Human DPH2 with a N terminal proprietary tag; Predicted MWt 79.90 kDa.
  • Specification
  • Gene Information
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Description : This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene.
Protein length : 489 amino acids
Molecular Weight : 79.900kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Strongly expressed in skeletal muscle. Moderately expressed in heart, small intestine, liver, pancreas, testis and colon. Weakly expressed in brain, placenta, kidney, speen, thymus, prostate, ovary and lymphocytes.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MESMFSSPAEAALQRETGVPGLLTPLPDLDGVYELERVAG FVRDLGCERVALQFPDQLLGDAVAVAARLEETTGSKMFIL GDTAYGSCCVDVLGAEQAGAQALIHFGPACLSPPARPLPV AFVLRQRSVALELCVKAFEAQNPDPKAPVVLLSEPACAHA LEALATLLRPRYLDLLVSSPAFPQPVGSLSPEPMPLERFG RRFPLAPGRRLEEYGAFYVGGSKASPDPDLDPDLSRLLLG WAPGQPFSSCCPDTGKTQDEGARAGRLRARRRYLVERARD ARVVGLLAGTLGVAQHREALAHLRNLTQAAGKRSYVLALG RPTPAKLANFPEVDVFVLLACPLGALAPQLSGSFFQPILA PCELEAACNPAWPPPGLAPHLTHYADLLPGSPFHVALPPP ESELWETPDVSLITGDLRPPPAWKSSNDHGSLALTPRPQL ELAESSPAASFLSSRSWQGLEPRLGQTPVTEAVSGRRGIA IAYEDEGSG
Sequence Similarities : Belongs to the DPH1/DPH2 family. DPH2 subfamily.
Gene Name : DPH2 DPH2 homolog (S. cerevisiae) [ Homo sapiens ]
Official Symbol : DPH2
Synonyms : DPH2; DPH2 homolog (S. cerevisiae); diptheria toxin resistance protein required for diphthamide biosynthesis like 2 (S. cerevisiae) , DPH2 like 2 (S. cerevisiae) , DPH2L2; diphthamide biosynthesis protein 2;
Gene ID : 1802
mRNA Refseq : NM_001039589
Protein Refseq : NP_001034678
MIM : 603456
Uniprot ID : Q9BQC3
Chromosome Location : 1p34

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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