Recombinant Mouse Synuclein, Alpha

Cat. No.: Snca-2730M
Product Overview: Recombinant mouse alpha-Synuclein, was expressed inE.coliand purified by using conventional chromatography techniques. MW =14.4 kDa (140aa), confirmed by MALDI-TOF.
Description: Alpha-Synuclein, also known as SNCA, an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-Synuclein has been suggested to be implicated in the pathogenesis of Parkinson.
Source: E.coli.
Sequences Of Amino Acids: MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVTTVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGNIAA ATGFVKKDQM GKGEEGYPQE GILEDMPVDP GSEAYEMPSE EGYQDYEPEA
Form: Liquid. In 20mM Tris-HCl buffer (pH 7.5) containing, 10% glycerol.
Purity: > 95% by SDS – PAGE.
Concentration: 1mg/ml (determined by BCA assay).
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: Snca synuclein, alpha [ Mus musculus ]
Synonyms: Snca; synuclein, alpha; NACP; alphaSYN; alpha-synuclein; alpha SYN; non-A4 component of amyloid; non-A beta component of AD amyloid
Gene ID: 20617
mRNA Refseq: NM_001042451
Protein Refseq: NP_001035916
UniProt ID: O55042
Chromosome Location: 6 B3; 6 29.0
Pathway: Alzheimer"s disease; Parkinson"s disease
Function: arachidonic acid binding; histone binding; identical protein binding; microtubule binding; phospholipase binding; phospholipid binding; protein N-terminus binding; protein domain specific binding

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