Recombinant Human ECI2, His-tagged

• Cat.No.: ECI2-29164TH
• Product Overview: Recombinant full length Human PECI with N terminal His tag; 384 amino acids with tag, MWt 42.3 kDa.

Specification

• Description: This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described.
• Protein length: 364 amino acids
• Conjugation: HIS
• Molecular Weight: 42.300kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMNRTA MRASQKDFENSMNQVKLLKKDPGNE VKLKLYALYKQATEGPCNMPKPGVF DLINKAKWDAWNALGSLPKEAARQN YVDLVSSLSPSLESSSQVEPGTDRK STGFETLVVTSEDGITKIMFNRPKK KNAINTEMYHEIMRALKAASKDDSI ITVLTGNGDYYSSGNDLTNFTDIPP GGVEEKAKNNAVLLREFVGCFIDFP KPLIAVVNGPAVGISVTLLGLFDAV YASDRATFHTPFSHLGQSPEGCSSY TFPKIMSPAKATEMLIFGKKLTAGE ACAQGLVTEVFPDSTFQKEVWTRLK AFAKLPPNALRISKEVIRKREREKL HAVNAEECNVLQGRWLSDECTNAVV NFLSRKSKL

Gene Information

• Gene Name: ECI2 enoyl-CoA delta isomerase 2 [ Homo sapiens ]
• Official Symbol: ECI2
• Synonyms: ECI2; enoyl-CoA delta isomerase 2; PECI, peroxisomal D3,D2 enoyl CoA isomerase; enoyl-CoA delta isomerase 2, mitochondrial; Hepatocellular carcinoma associated antigen 88; ACBD2; acyl Coenzyme A binding domain containing 2; DRS1; HCA88
• Gene ID: 10455
• mRNA Refseq: NM_006117
• Protein Refseq: NP_006108
• MIM: 608024
• Uniprot ID: O75521
• Chromosome Location: 6p24.3
• Pathway: Fatty acid metabolism, organism-specific biosystem; Fatty acid metabolism, conserved biosystem; Peroxisome, organism-specific biosystem; Peroxisome, conserved biosystem
• Function: binding; dodecenoyl-CoA delta-isomerase activity; dodecenoyl-CoA delta-isomerase activity; fatty-acyl-CoA binding; isomerase activity