Recombinant Human ELF5

• Cat.No.: ELF5-28286TH
• Product Overview: Recombinant fragment of Human ELF5 with N terminal proprietary tag. Predicted MW 36.41 kDa.

Specification

• Description: The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Protein length: 98 amino acids
• Molecular Weight: 36.410kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Expressed exclusively in tissues with a high content of epithelial cells. Highly expressed in salivary gland, mammary gland, kidney and prostate. Weakly expressed in placenta and lung. Isoform 1 and isoform 2 are differentially expressed in different tiss
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: SRTSLQSSHLWEFVRDLLLSPEENC GILEWEDREQGIFRVVKSEALAKMW GQRKKNDRMTYEKLSRALRYYYKTG ILERVDRRLVYKFGKNAHGWQED
• Sequence Similarities: Belongs to the ETS family.Contains 1 ETS DNA-binding domain.Contains 1 PNT (pointed) domain.

Gene Information

• Gene Name: ELF5 E74-like factor 5 (ets domain transcription factor) [ Homo sapiens ]
• Official Symbol: ELF5
• Synonyms: ELF5; E74-like factor 5 (ets domain transcription factor); ETS-related transcription factor Elf-5
• Gene ID: 2001
• mRNA Refseq: NM_001243080
• Protein Refseq: NP_001230009
• MIM: 605169
• Uniprot ID: Q9UKW6
• Chromosome Location: 11p13-p12
• Function: sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity