Recombinant Human EPAS1
Cat.No. : | EPAS1-29318TH |
Product Overview : | Recombinant fragment (amino acids 28-347) of Human HIF2 alpha with proprietary tag at the N terminal; Predicted MW 60.83 kDa, inclusive of tag. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. |
Protein length : | 320 amino acids |
Molecular Weight : | 60.830kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Expressed in most tissues, with highest levels in placenta, lung and heart. Selectively expressed in endothelial cells. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | SKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTH KLLSSVCSENESEAEADQQMDNLYLKALEGFIAVVTQDGD MIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENL SLKNGSGFGKKSKDMSTERDFFMRMKCTVTNRGRTVNLKS ATWKVLHCTGQVKVYNNCPPHNSLCGYKEPLLSCLIIMCE PIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRITELIGY HPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVVSGQY RMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEI |
Sequence Similarities : | Contains 1 basic helix-loop-helix (bHLH) domain.Contains 1 PAC (PAS-associated C-terminal) domain.Contains 2 PAS (PER-ARNT-SIM) domains. |
Gene Name : | EPAS1 endothelial PAS domain protein 1 [ Homo sapiens ] |
Official Symbol : | EPAS1 |
Synonyms : | EPAS1; endothelial PAS domain protein 1; endothelial PAS domain-containing protein 1; bHLHe73; HIF 1 alpha like factor; HIF2A; HLF; MOP2; PASD2; |
Gene ID : | 2034 |
mRNA Refseq : | NM_001430 |
Protein Refseq : | NP_001421 |
MIM : | 603349 |
Uniprot ID : | Q99814 |
Chromosome Location : | 2p21-p16 |
Pathway : | Adipogenesis, organism-specific biosystem; HIF-2-alpha transcription factor network, organism-specific biosystem; Pathways in cancer, organism-specific biosystem; Renal cell carcinoma, organism-specific biosystem; Renal cell carcinoma, conserved biosystem; |
Function : | DNA binding; histone acetyltransferase binding; protein binding; protein heterodimerization activity; contributes_to sequence-specific DNA binding; |
Products Types
◆ Recombinant Protein | ||
EPAS1-2173H | Recombinant Human EPAS1 Protein, His-tagged | +Inquiry |
EPAS1-3349H | Recombinant Human EPAS1 Protein, GST-tagged | +Inquiry |
EPAS1-2808M | Recombinant Mouse EPAS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
EPAS1-1772R | Recombinant Rat EPAS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
EPAS1-12475H | Recombinant Human EPAS1, GST-tagged | +Inquiry |
◆ Lysates | ||
EPAS1-6588HCL | Recombinant Human EPAS1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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