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Recombinant Human ETFB, His-tagged

Cat.No.: ETFB-28404TH
Product Overview: Recombinant full length Human ETFB with an N terminal His tag; 275 amino acids, predicted MWt 30kDa.
Description: This gene encodes electron-transfer-flavoprotein, beta polypeptide, which shuttles electrons between primary flavoprotein dehydrogenases involved in mitochondrial fatty acid and amino acid catabolism and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. The gene deficiencies have been implicated in type II glutaricaciduria. Alternatively spliced transcript variants have been found for this gene.
Protein length: 255 amino acids
Conjugation: HIS
Molecular Weight: 30.000kDa inclusive of tags
Source: E. coli
Tissue specificity: Abundant in liver, heart and skeletal muscle. A weak expression is seen in the brain, placenta, lung, kidney and pancreas.
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 40% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, pH 8.0
Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMAELRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAVVTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVETTEDLVAKLKEIGRI
Sequence Similarities: Belongs to the ETF beta-subunit/fixA family.
Gene Name: ETFB electron-transfer-flavoprotein, beta polypeptide [ Homo sapiens ]
Official Symbol: ETFB
Synonyms: ETFB; electron-transfer-flavoprotein, beta polypeptide; electron transfer flavoprotein subunit beta;
Gene ID: 2109
mRNA Refseq: NM_001014763
Protein Refseq: NP_001014763
MIM: 130410
Uniprot ID: P38117
Chromosome Location: 19q13.3-q13.4
Pathway: Metabolism, organism-specific biosystem; Respiratory electron transport, organism-specific biosystem; Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins., organism-specific biosystem; The citric acid (TCA) cycle and respiratory electron transport, organism-specific biosystem;
Function: electron carrier activity;

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