Recombinant Human FBP1, His-tagged

• Cat.No.: FBP1-28810TH
• Product Overview: Recombinant full length human FBP1 fused to His-tag at N-terminus; amino acids 1-338 , 39.0kDa.

Specification

• Description: Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.
• Conjugation: HIS
• Source: E. coli
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: FBP1-28810TH is purified using conventional chromatography techniques.
• Sequence Similarities: Belongs to the FBPase class 1 family.

Gene Information

• Gene Name: FBP1 fructose-1,6-bisphosphatase 1 [ Homo sapiens ]
• Official Symbol: FBP1
• Synonyms: FBP1; fructose-1,6-bisphosphatase 1; FBP
• Gene ID: 2203
• mRNA Refseq: NM_000507
• Protein Refseq: NP_000498
• MIM: 611570
• Uniprot ID: P09467
• Chromosome Location: 9q22.3
• Pathway: Fructose and mannose metabolism, organism-specific biosystem; Fructose and mannose metabolism, conserved biosystem; Gluconeogenesis, organism-specific biosystem; Gluconeogenesis, oxaloacetate => fructose-6P, organism-specific biosystem
• Function: AMP binding; fructose 1,6-bisphosphate 1-phosphatase activity; fructose 1,6-bisphosphate 1-phosphatase activity; fructose 1,6-bisphosphate 1-phosphatase activity; hydrolase activity