"FOSB" Related Products

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Recombinant Human FOSB

Cat.No.: FOSB-28107TH
Product Overview: Recombinant fragment, corresponding to amino acids 113-151 of Human Fos B
Description: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Source: E. coli
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: SSGGASGSGGPSTSGTTSGPGPARPARARPRRPREETLT
Sequence Similarities: Belongs to the bZIP family. Fos subfamily.Contains 1 bZIP domain.
Gene Name: FOSB FBJ murine osteosarcoma viral oncogene homolog B [ Homo sapiens ]
Official Symbol: FOSB
Synonyms: FOSB; FBJ murine osteosarcoma viral oncogene homolog B; protein fosB; activator protein 1; AP 1; DKFZp686C0818; GOS3; GOSB; G0S3; MGC42291; oncogene FOS B;
Gene ID: 2354
mRNA Refseq: NM_001114171
Protein Refseq: NP_001107643
MIM: 164772
Uniprot ID: P53539
Chromosome Location: 19q13.3
Pathway: Osteoclast differentiation, organism-specific biosystem; Osteoclast differentiation, conserved biosystem; TGF-beta Receptor Signaling Pathway, organism-specific biosystem;
Function: DNA binding; protein dimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor binding;

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