Recombinant Human GAB1, His-tagged GAB1-27493TH

Recombinant Human GAB1, His-tagged


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Recombinant Human GAB1, His-tagged

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Cat.No. : GAB1-27493TH
Product Overview : Recombinant full length Human GAB1 with N-terminal His tag expressed in a Baculovirus infected Sf9 cell expression system, MWt 108kDa.
Description : The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.
Conjugation : HIS
Form : Liquid
Storage buffer : Preservative: 150mM ImidazoleConstituents: 25% Glycerol, 50mM Sodium phosphate, 300mM Sodium chloride, 2mM DTT, 0.1mM PMSF, pH 7.0
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the GAB family.Contains 1 PH domain.
Gene Name : GAB1 GRB2-associated binding protein 1 [ Homo sapiens ]
Official Symbol : GAB1
Synonyms : GAB1; GRB2-associated binding protein 1; GRB2-associated-binding protein 1;
Gene ID : 2549
mRNA Refseq : NM_002039
Protein Refseq : NP_002030
MIM : 604439
Uniprot ID : Q13480
Chromosome Location : 4q31.1
Pathway : B Cell Receptor Signaling Pathway, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem; Downstream signaling of activated FGFR, organism-specific biosystem; EGF receptor (ErbB1) signaling pathway, organism-specific biosystem;
Function : SH3/SH2 adaptor activity; protein binding;

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