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Recombinant Human GALT, His-tagged

Cat.No. : GALT-27306TH
Product Overview : Recombinant fragment, corresponding to amino acids 1-313 of Human GALT with N terminal His tag; 313 amino acids, 36kDa.
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Description : Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined.
Conjugation : HIS
Source : E. coli
Form : Lyophilised:Reconstitute with 141 μl aqua dest.
Storage buffer : Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MSRSGTDPQQRQQASEADAAAATFR ANDHQHIRYNPLQDE WVLVSAHRMKRPWQGQVEPQLLKTV PRHDPLNPLCPGA IRANGEVNPQYDSTFLFDNDFPALQ PDAPSPGPSDHPLFQAKSARGVCKV MCFHPWSDVTLPLMSVPEIRAVVDA WAS VTEELGAQYPWVQIFENKGAMMGCS NPHPHCQVWASSF LPDIAQREERSQQAYKSQHGEPLLM EYSRQELLRKERLVL TSEHWLVLVPFWATWPYQTLLLPRR HVRRLPELTPAER DDLASIMKKLLTKYDNLFETSFPYS MGWHGAPTGSEAG ANW
Sequence Similarities : Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
Gene Name : GALT galactose-1-phosphate uridylyltransferase [ Homo sapiens ]
Official Symbol : GALT
Synonyms : GALT; galactose-1-phosphate uridylyltransferase;
Gene ID : 2592
mRNA Refseq : NM_000155
Protein Refseq : NP_000146
MIM : 606999
Uniprot ID : P07902
Chromosome Location : 9p13
Pathway : Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Galactose catabolism, organism-specific biosystem; Galactose metabolism, organism-specific biosystem; Galactose metabolism, conserved biosystem;
Function : UDP-glucose:hexose-1-phosphate uridylyltransferase activity; metal ion binding; nucleotidyltransferase activity; transferase activity; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is GALT protein deficiency treated? 02/14/2023

Treatment for GALT deficiency involves a strict lactose-free diet, which means avoiding milk, dairy products, and other foods containing galactose.

Are there any specific dietary recommendations for individuals with GALT deficiency? 11/22/2021

Individuals with GALT deficiency are recommended to avoid galactose-containing foods, and dietary supplementation with essential nutrients may be necessary.

Can GALT deficiency lead to long-term complications? 02/13/2019

Yes, if left untreated, GALT deficiency can lead to long-term complications such as liver damage, cognitive impairment, and reproductive issues.

Can GALT protein levels be measured in the blood? 07/05/2017

Yes, GALT enzyme activity levels can be measured in the blood to diagnose GALT deficiency.

What are the symptoms of galactosemia? 02/27/2017

Symptoms of galactosemia include jaundice, poor feeding, vomiting, liver enlargement, and failure to thrive in infants. In older children and adults, symptoms may include cognitive impairment, speech difficulties, and ovarian insufficiency in females.

Customer Reviews (3)

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Reviews
12/19/2022

    The GALT Protein is an exceptional product that fully meets my experimental needs.

    02/10/2022

      Its versatility and reliability make it a top choice for researchers in various fields.

      10/20/2016

        The GALT Protein's adaptability has significantly expanded the scope of my investigations and broadened the possibilities for my research.

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