Recombinant Human GALT, His-tagged
Cat.No. : | GALT-27306TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 1-313 of Human GALT with N terminal His tag; 313 amino acids, 36kDa. |
- Specification
- Gene Information
- Related Products
Description : | Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. |
Conjugation : | HIS |
Source : | E. coli |
Form : | Lyophilised:Reconstitute with 141 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MSRSGTDPQQRQQASEADAAAATFR ANDHQHIRYNPLQDE WVLVSAHRMKRPWQGQVEPQLLKTV PRHDPLNPLCPGA IRANGEVNPQYDSTFLFDNDFPALQ PDAPSPGPSDHPLFQAKSARGVCKV MCFHPWSDVTLPLMSVPEIRAVVDA WAS VTEELGAQYPWVQIFENKGAMMGCS NPHPHCQVWASSF LPDIAQREERSQQAYKSQHGEPLLM EYSRQELLRKERLVL TSEHWLVLVPFWATWPYQTLLLPRR HVRRLPELTPAER DDLASIMKKLLTKYDNLFETSFPYS MGWHGAPTGSEAG ANW |
Sequence Similarities : | Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. |
Gene Name : | GALT galactose-1-phosphate uridylyltransferase [ Homo sapiens ] |
Official Symbol : | GALT |
Synonyms : | GALT; galactose-1-phosphate uridylyltransferase; |
Gene ID : | 2592 |
mRNA Refseq : | NM_000155 |
Protein Refseq : | NP_000146 |
MIM : | 606999 |
Uniprot ID : | P07902 |
Chromosome Location : | 9p13 |
Pathway : | Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Galactose catabolism, organism-specific biosystem; Galactose metabolism, organism-specific biosystem; Galactose metabolism, conserved biosystem; |
Function : | UDP-glucose:hexose-1-phosphate uridylyltransferase activity; metal ion binding; nucleotidyltransferase activity; transferase activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
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Galt-3146M | Recombinant Mouse Galt Protein, Myc/DDK-tagged | +Inquiry |
GALT-0846B | Recombinant Bacillus subtilis GALT protein, His-tagged | +Inquiry |
GALT-2474R | Recombinant Rat GALT Protein | +Inquiry |
◆ Native Protein | ||
GALT-10 | Active Native Streptoverticillium mobaraense | +Inquiry |
◆ Lysates | ||
GALT-6026HCL | Recombinant Human GALT 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (5)
Ask a questionTreatment for GALT deficiency involves a strict lactose-free diet, which means avoiding milk, dairy products, and other foods containing galactose.
Individuals with GALT deficiency are recommended to avoid galactose-containing foods, and dietary supplementation with essential nutrients may be necessary.
Yes, if left untreated, GALT deficiency can lead to long-term complications such as liver damage, cognitive impairment, and reproductive issues.
Yes, GALT enzyme activity levels can be measured in the blood to diagnose GALT deficiency.
Symptoms of galactosemia include jaundice, poor feeding, vomiting, liver enlargement, and failure to thrive in infants. In older children and adults, symptoms may include cognitive impairment, speech difficulties, and ovarian insufficiency in females.
Customer Reviews (3)
Write a reviewThe GALT Protein is an exceptional product that fully meets my experimental needs.
Its versatility and reliability make it a top choice for researchers in various fields.
The GALT Protein's adaptability has significantly expanded the scope of my investigations and broadened the possibilities for my research.
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