||Recombinant fragment, corresponding to amino acids 1-313 of Human GALT with N terminal His tag; 313 amino acids, 36kDa.
||Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined.
||Lyophilised:Reconstitute with 141 μl aqua dest.
||Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
||Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
|Sequences of amino acids:
||MSRSGTDPQQRQQASEADAAAATFRANDHQHIRYNPLQDE WVLVSAHRMKRPWQGQVEPQLLKTVPRHDPLNPLCPGA IRANGEVNPQYDSTFLFDNDFPALQPDAPSPGPSDHPLFQAKSARGVCKVMCFHPWSDVTLPLMSVPEIRAVVDAWAS VTEELGAQYPWVQIFENKGAMMGCSNPHPHCQVWASSF LPDIAQREERSQQAYKSQHGEPLLMEYSRQELLRKERLVL TSEHWLVLVPFWATWPYQTLLLPRRHVRRLPELTPAER DDLASIMKKLLTKYDNLFETSFPYSMGWHGAPTGSEAG ANW
||Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.