Recombinant Human GIP

• Cat.No.: GIP-29064TH
• Product Overview: Recombinant full length Human GIP with a proprietary tag; Predicted MWt 42.9 kDa.

Specification

• Description: This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion.
• Protein length: 153 amino acids
• Molecular Weight: 42.900kDa inclusive of tags
• Source: Wheat germ
• Biological activity: useful for Antibody Production and Protein Array
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.31% Glutathione
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MVATKTFALLLLSLFLAVGLGEKKE GHFSALPSLPVGSHAKVSSPQPRGP RYAEGTFISDYSIAMDKIHQQDFVN WLLAQKGKKNDWKHNITQREARALE LASQANRKEEEAVEPQSSPAKNPSD EDLLRDLLIQELLACLLDQTNLCRL RSR

Gene Information

• Gene Name: GIP gastric inhibitory polypeptide [ Homo sapiens ]
• Official Symbol: GIP
• Synonyms: GIP; gastric inhibitory polypeptide; glucose dependent insulinotropic polypeptide
• Gene ID: 2695
• mRNA Refseq: NM_004123
• Protein Refseq: NP_004114
• MIM: 137240
• Uniprot ID: P09681
• Chromosome Location: 17q21.3-q22
• Pathway: Class B/2 (Secretin family receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Glucagon-type ligand receptors, organism-specific biosystem
• Function: hormone activity