Recombinant Human Ephrin-A4

• Cat.No.: EFNA4-1610H

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Non
• Description: Ephrin-A4 is a glycoinositol phospholipid membrane anchor containing ephrin found in variety of adult tissue such as kidney, lung, colon and ovary. Ephrin-A4 is a ligand for the erythropoietin-producing hepatocellular (Eph) receptor family of tyrosine kinases. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Ephrin-A4 encodes an EFNA class ephrin. Ephrin-A4 (s) may play a role in the interaction between activated B lymphocytes and dendritic cells in human tonsils.
• Molecular Weight: The predicted molecular weight of Recombinant Human Ephrin-A4 is 43.7 kDa. However, the actual molecular weight as observed by migration on SDS Page is 50 kDa.
• State Of Matter: Lyophilized.
• Purity: >90% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Storage: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: EFNA4 ephrin-A4 [ Homo sapiens ]
• Synonyms: EFNA4; ephrin-A4; EFL4; EPLG4; LERK4; MGC125826; ligand of eph-related kinase 4; eph-related receptor tyrosine kinase ligand 4; LERK-4; OTTHUMP00000033237; OTTHUMP00000033238; ephrin A4
• Gene ID: 1945
• mRNA Refseq: NM_005227
• Protein Refseq: NP_005218
• MIM: 601380
• UniProt ID: P52798
• Chromosome Location: 1q21-q22
• Pathway: Axon guidance
• Function: transmembrane-ephrin receptor activity