Recombinant Human GNB2L1, His-tagged GNB2L1-30327TH

Recombinant Human GNB2L1, His-tagged

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Recombinant Human GNB2L1, His-tagged

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Cat.No. : GNB2L1-30327TH
Product Overview : Recombinant full length Human RACK1 protein with an N terminal His tag. Observed MWt: 37kDa.
Description : Seems to bind protein kinase C acting as an intracellular receptor to anchor the activated PKC to the cytoskeleton. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1.
Conjugation : HIS
Source : E. coli
Form : Lyophilised:Reconstitute with 87 μl aqua dest.
Storage buffer : Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTI IMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFA LSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRF SPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGY LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD IINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQ EVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVW QVTIGTR
Sequence Similarities : Belongs to the WD repeat G protein beta family.Contains 7 WD repeats.
Gene Name : GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 [ Homo sapiens ]
Official Symbol : GNB2L1
Synonyms : GNB2L1; guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1; guanine nucleotide-binding protein subunit beta-2-like 1; Gnb2 rs1; H12.3; RACK1; Receptor for Activated C Kinase 1;
Gene ID : 10399
mRNA Refseq : NM_006098
Protein Refseq : NP_006089
MIM : 176981
Uniprot ID : P63244
Chromosome Location : 5q35.3
Pathway : CXCR4-mediated signaling events, organism-specific biosystem; Hypoxic and oxygen homeostasis regulation of HIF-1-alpha, organism-specific biosystem; IGF1 pathway, organism-specific biosystem; IL-2 Signaling Pathway, organism-specific biosystem; IL-3 Signaling Pathway, organism-specific biosystem;
Function : SH2 domain binding; ion channel inhibitor activity; protein binding; protein kinase C binding; protein phosphatase binding;

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