Recombinant Human GPLD1

• Cat.No.: GPLD1-27985TH
• Product Overview: Recombinant full length Human GPLD1 Isoform 2 with N terminal proprietary tag; Predicted MW 45.47 kDa.

Specification

• Description: Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane.
• Protein length: 176 amino acids
• Molecular Weight: 45.470kDa inclusive of tags
• Source: Wheat germ
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MSAFRLWPGLLIMLGSLCHRGSPCGLSTHIEIGHRALEFL QLHNGRVNYRELLLEHQDAYQAGIVFPDCFYPSICKGGKF HDVSESTHWTPFLNASVHYIRENYPLPWEKDTEKLVAFLF GITSHMAADVSWHSLGLEQGFLRTMGAIDFHGSYSEAHSA GDFGTVYLHLLNFLVV
• Sequence Similarities: Belongs to the GPLD1 family.Contains 7 FG-GAP repeats.

Gene Information

• Gene Name: GPLD1 glycosylphosphatidylinositol specific phospholipase D1 [ Homo sapiens ]
• Official Symbol: GPLD1
• Synonyms: GPLD1; glycosylphosphatidylinositol specific phospholipase D1; phosphatidylinositol-glycan-specific phospholipase D
• Gene ID: 2822
• mRNA Refseq: NM_001503
• Protein Refseq: NP_001494
• MIM: 602515
• Uniprot ID: P80108
• Chromosome Location: 6p22.1
• Pathway: Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, organism-specific biosystem; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, conserved biosystem
• Function: glycosylphosphatidylinositol phospholipase D activity; hydrolase activity; phospholipase D activity