"EPHA1" Related Products


Recombinant Human EPH Receptor A1

Cat. No.: EPHA1-1608H
Description: EPH receptor A1, also known as EPHA1 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA1 is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
Source: NSO cells.
Molecular Weight: The predicted molecular weight of Recombinant Human EphA1 is 84 kDa. However, the actual molecular weight as observed by migration on SDS Page is 110 kDa.
State Of Matter: Lyophilized.
Purity: >97% by SDS Page and analyzed by silver stain.
Endotoxin: <1.0 EU/µg as determined by the LAL method.
Storage: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name: EPHA1 EPH receptor A1 [ Homo sapiens ]
Synonyms: EPHA1; EPH receptor A1; EPH; EPHT; EPHT1; MGC163163; EphA1; EC; Tyrosine-protein kinase receptor EPH; eph tyrosine kinase 1; ephrin receptor EphA1; ephrin type-A receptor 1; erythropoietin-producing hepatoma amplified sequence; oncogene EPH; soluble EPHA1 variant 1; soluble EPHA1 variant 2
Gene ID: 2041
mRNA Refseq: NM_005232
Protein Refseq: NP_005223
MIM: 179610
UniProt ID: P21709
Chromosome Location: 7q32-q36
Pathway: Axon guidance
Function: ephrin receptor activity; nucleotide binding; protein binding; receptor activity; transferase activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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