Recombinant Human GTF2H1, His-tagged

• Cat.No.: GTF2H1-28281TH
• Product Overview: Recombinant full length His tagged human GTF2H1 isolated from an E. coli strain that carries the coding sequence of the protein under the control of a T7 promoter.

Specification

• Description: General transcription factor IIH subunit 1 is a protein that in humans is encoded by the GTF2H1 gene.
• Conjugation: HIS
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Contains 2 BSD domains.

Gene Information

• Gene Name: GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa [ Homo sapiens ]
• Official Symbol: GTF2H1
• Synonyms: GTF2H1; general transcription factor IIH, polypeptide 1, 62kDa; general transcription factor IIH, polypeptide 1 (62kD subunit); general transcription factor IIH subunit 1; BTF2
• Gene ID: 2965
• mRNA Refseq: NM_001142307
• Protein Refseq: NP_001135779
• MIM: 189972
• Uniprot ID: P32780
• Chromosome Location: 11p15.1-p14
• Pathway: Androgen Receptor Signaling Pathway, organism-specific biosystem; Basal transcription factors, organism-specific biosystem; Basal transcription factors, conserved biosystem; DNA Repair, organism-specific biosystem; Dual incision reaction in GG-NER, organism-specific biosystem
• Function: contributes_to DNA-dependent ATPase activity; contributes_to RNA polymerase II carboxy-terminal domain kinase activity; protein binding; contributes_to protein kinase activity