"HBA2" Related Products

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Native Human HBA2

Cat.No.: HBA2-27784TH
Product Overview: Full length Hemoglobin A1c purified from Human Erythrocytes, Predicted MWt 15 kDa.
Description: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5 untranslated regions and the introns, but they differ significantly over the 3 untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
Source: Human Erythrocytes
Species: Human
Form: Liquid
Molecular Mass: 15 kDa
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80°C . Avoid freeze / thaw cycles.
Storage Buffer: Preservative: NoneConstituents: 50mM Sodium phosphate, pH 8.0
Gene Name: HBA2 hemoglobin, alpha 2 [ Homo sapiens ]
Official Symbol: HBA2
Synonyms: HBA2; hemoglobin, alpha 2; hemoglobin subunit alpha; alpha globin; alpha-globin; alpha-2 globin; hemoglobin alpha chain; HBH;
Gene ID: 3040
mRNA Refseq: NM_000517
Protein Refseq: NP_000508
MIM: 141850
UniProt ID: P69905
Chromosome Location: 16p13.3
Pathway: African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Malaria, organism-specific biosystem; Malaria, conserved biosystem; Selenium Pathway, organism-specific biosystem;
Function: contributes_to haptoglobin binding; heme binding; metal ion binding; oxygen binding; oxygen transporter activity; contributes_to peroxidase activity; protein binding;

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