||Recombinant fragment, corresponding to amino acids 1-481 of Human HDAC10 with N-terminal proprietary tag expressed in a Baculovirus expression system, 79 kDa.
||The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
||Ubiquitous. High expression in liver, spleen, pancreas and kidney.
||Specific Activity: 1.6 pmol/min/ug.Assay condition : 25 mM Tris/Cl, pH8.0, 137 mM NaCl, 2.7 mM KCl, 1 mM MgCl2, and 0.1 mg/ml BSA, 20 uM BPS HDAC substrate, and 20 ng/ul HDAC10. Incubation condition: 30 min at 37oC.
||Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0
||Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
||Belongs to the histone deacetylase family. HD type 2 subfamily.