"HEY1" Related Products


Recombinant Human HEY1, His-tagged

Cat.No.: HEY1-29230TH
Product Overview: Recombinant full length protein, corresponding to amino acids 1-304 of Human HEY1, His-Tag at N-terminus.
Description: This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants.
Conjugation: HIS
Source: E. coli
Tissue specificity: Expressed in the somitic mesoderm, the central nervous system, the kidney, the heart, nasal epithelium, and limbs.
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: 0.002% Sodium AzideConstituents: 0.1% Triton-X-100, 10mM Tris, 10mM DTT, pH 8.0
Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities: Belongs to the HEY family.Contains 1 basic helix-loop-helix (bHLH) domain.Contains 1 Orange domain.
Gene Name: HEY1 hairy/enhancer-of-split related with YRPW motif 1 [ Homo sapiens ]
Official Symbol: HEY1
Synonyms: HEY1; hairy/enhancer-of-split related with YRPW motif 1; hairy/enhancer-of-split related with YRPW motif protein 1; BHLHb31; CHF 2; CHF2; HERP2; HESR 1; HESR1; HRT 1;
Gene ID: 23462
mRNA Refseq: NM_001040708
Protein Refseq: NP_001035798
MIM: 602953
Uniprot ID: Q9Y5J3
Chromosome Location: 8q21
Pathway: Delta-Notch Signaling Pathway, organism-specific biosystem; Heart Development, organism-specific biosystem; Notch-mediated HES/HEY network, organism-specific biosystem;
Function: DNA binding; RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; microsatellite binding; protein binding; protein binding transcription factor activity;

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