"GFRA3" Related Products

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Recombinant Human GDNF Family Receptor Alpha 3

Cat. No.: GFRA3-1620H
Description: GDNF family receptor alpha 3, also known as GFRA3 is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. GFRalpha3 preferentially binds the newest member of the glial-derived neurotrophic factor family of ligands, artemin. The major site of GFRalpha3 expression is in the dorsal root ganglion. GFRalpha3 artemin neurons are immunopositive for markers expected of nociceptors and include a subset of neurons distinct from the GDNF-responsive population.
Source: Sf 21 Insect Cells.
State Of Matter: Lyophilized.
Purity: >90% by SDS Page and analyzed by silver stain.
Endotoxin: <1.0 EU/µg as determined by the LAL method.
Molecular Weight: The predicted molecular weight of Recombinant Human GFRα-3 is Mr 67 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 67 kDa.
Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Gene Name: GFRA3 GDNF family receptor alpha 3 [ Homo sapiens ]
Synonyms: GDNF family receptor alpha 3; GFRA3; GPI-linked receptor; glial cell line-derived neurotrophic factor receptor alpha-3; GFR-alpha-3; GFRa-3
Gene ID: 2676
mRNA Refseq: NM_001496
Protein Refseq: NP_001487
MIM: 605710
UniProt ID: O60609
Chromosome Location: 5q31.1-q31.3
Function: axon guidance receptor activity; receptor activity; receptor binding

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