Recombinant Human ID4
Cat.No. : | ID4-28078TH |
Product Overview : | Recombinant full length Human ID4 with N terminal proprietary tag; Predicted MWt 43.78 kDa inclusive of tag. |
- Specification
- Gene Information
- Related Products
Description : | Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins (Pagliuca et al. |
Protein length : | 161 amino acids |
Molecular Weight : | 43.780kDa inclusive of tags |
Source : | Wheat germ |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MKAVSPVRPSGRKAPSGCGGGELALRCLAEHGHSLGGSAA AAAAAAAARCKAAEAAADEPALCLQCDMNDCYSRLRRLVP TIPPNKKVSKVEILQHVIDYILDLQLALETHPALLRQPPP PAPPHHPAGTCPAAPPRTPLTALNTDPAGAVNKQGDSILC R |
Sequence Similarities : | Contains 1 basic helix-loop-helix (bHLH) domain. |
Gene Name : | ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein [ Homo sapiens ] |
Official Symbol : | ID4 |
Synonyms : | ID4; inhibitor of DNA binding 4, dominant negative helix-loop-helix protein; DNA-binding protein inhibitor ID-4; bHLHb27; |
Gene ID : | 3400 |
mRNA Refseq : | NM_001546 |
Protein Refseq : | NP_001537 |
MIM : | 600581 |
Uniprot ID : | P47928 |
Chromosome Location : | 6p22.3 |
Pathway : | Id Signaling Pathway, organism-specific biosystem; TGF-beta signaling pathway, organism-specific biosystem; TGF-beta signaling pathway, conserved biosystem; |
Function : | RNA polymerase II transcription factor binding; protein binding; transcription corepressor activity; |
Products Types
◆ Recombinant Protein | ||
ID4-4408M | Recombinant Mouse ID4 Protein, His (Fc)-Avi-tagged | +Inquiry |
ID4-2010R | Recombinant Rhesus Macaque ID4 Protein, His (Fc)-Avi-tagged | +Inquiry |
Id4-1210M | Recombinant Mouse Id4 Protein, MYC/DDK-tagged | +Inquiry |
ID4-3700Z | Recombinant Zebrafish ID4 | +Inquiry |
ID4-5855C | Recombinant Chicken ID4 | +Inquiry |
◆ Lysates | ||
ID4-5309HCL | Recombinant Human ID4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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