Native Human LDHA


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Native Human LDHA

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Cat.No. : LDHA-26867TH
Product Overview : Full length native Lactate Dehydrogenase Isoenzyme V purified from human liver.
Description : The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene.
Biological activity : Activity:1140 Unit/ml @ 37°C Dimension. Specific Activity:157 Units/mg protein. One unit will catalyze the transformation of one micromole of Lactate to pyruvate at 37°C and pH 8.55
Form : Liquid
Purity : Ammonium Sulphate Precipitation
Storage buffer : Preservative: NoneConstituents: 50mM Tris-Chloride, 1mM EDTA, 1mM DTE, pH 8.3
Storage : Store at +4°C. Do not freeze.
Gene Name : LDHA lactate dehydrogenase A [ Homo sapiens ]
Official Symbol : LDHA
Synonyms : LDHA; lactate dehydrogenase A; L-lactate dehydrogenase A chain;
Gene ID : 3939
mRNA Refseq : NM_001135239
Protein Refseq : NP_001128711
MIM : 150000
Uniprot ID : P00338
Chromosome Location : 11p15.1
Pathway : Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Glycolysis / Gluconeogenesis, organism-specific biosystem; Glycolysis / Gluconeogenesis, conserved biosystem; Glycolysis and Gluconeogenesis, organism-specific biosystem;
Function : L-lactate dehydrogenase activity; nucleotide binding; oxidoreductase activity;

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