"LMNB1" Related Products

Expand
Expand

Recombinant Human LMNB1

Cat.No.: LMNB1-29911TH
Product Overview: Recombinant fragment corresponding to amino acids 107-186 of Human Lamin B1 with a N terminal proprietary tag; predicted MWt 34.43 kDa inclusive of tag.
Description: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).
Protein length: 80 amino acids
Molecular Weight: 34.430kDa inclusive of tags
Source: Wheat germ
Form: Liquid
Purity: Proprietary Purification
Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids: LGKCKAEHDQLLLNYAKKESDLNGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLAAAKKQLAD
Sequence Similarities: Belongs to the intermediate filament family.
Gene Name: LMNB1 lamin B1 [ Homo sapiens ]
Official Symbol: LMNB1
Synonyms: LMNB1; lamin B1; lamin-B1;
Gene ID: 4001
mRNA Refseq: NM_001198557
Protein Refseq: NP_001185486
MIM: 150340
Uniprot ID: P20700
Chromosome Location: 5q23.2
Pathway: Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; Breakdown of the nuclear lamina, organism-specific biosystem; Caspase cascade in apoptosis, organism-specific biosystem;
Function: phospholipase binding; structural molecule activity;

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.