Recombinant Human MAN1A1

• Cat.No.: MAN1A1-27144TH
• Product Overview: Recombinant fragment of Human alpha 1,2 Mannosidase IA (aa 110-199) with a N terminal proprietary tag: predicted molecular weight 35.53 kDa.

Specification

• Description: This gene encodes a class I mammalian Golgi 1,2-mannosidase which is a type II transmembrane protein. This protein catalyzes the removal of 3 distinct mannose residues from peptide-bound Man(9)-GlcNAc(2) oligosaccharides and belongs to family 47 of glycosyl hydrolases.
• Protein length: 90 amino acids
• Molecular Weight: 35.530kDa inclusive of tags
• Source: Wheat germ
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: PGDPEAALEDNLARIRENHERALRE AKETLQKLPEEIQRDILLEKKKVAQ DQLRDKAPFRGLPPVDFVPPIGVES REPADAAIREKRAKI
• Sequence Similarities: Belongs to the glycosyl hydrolase 47 family.

Gene Information

• Gene Name: MAN1A1 mannosidase, alpha, class 1A, member 1 [ Homo sapiens ]
• Official Symbol: MAN1A1
• Synonyms: MAN1A1; mannosidase, alpha, class 1A, member 1; mannosyl-oligosaccharide 1,2-alpha-mannosidase IA
• Gene ID: 4121
• mRNA Refseq: NM_005907
• Protein Refseq: NP_005898
• MIM: 604344
• Uniprot ID: P33908
• Chromosome Location: 6q22
• Pathway: Asparagine N-linked glycosylation, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; N-Glycan biosynthesis, organism-specific biosystem; N-Glycan biosynthesis, conserved biosystem
• Function: calcium ion binding; hydrolase activity, acting on glycosyl bonds; mannosidase activity; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity