Recombinant Human MARK3

• Cat.No.: MARK3-26831TH
• Product Overview: Recombinant full length Mark3 protein (Human), with N-terminal enzyme tag, MW 110kDa. Expressed by baculovirus in insect sf9 cells.

Specification

• Description: The protein encoded by this gene is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for this gene.
• Tissue specificity: Ubiquitous.
• Biological activity: Specific activity 722 nmol/min/mg.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. MARK subfamily.Contains 1 KA1 (kinase-associated) domain.Contains 1 protein kinase domain.Contains 1 UBA domain.

Gene Information

• Gene Name: MARK3 MAP/microtubule affinity-regulating kinase 3 [ Homo sapiens ]
• Official Symbol: MARK3
• Synonyms: MARK3; MAP/microtubule affinity-regulating kinase 3; CTAK1; KP78
• Gene ID: 4140
• mRNA Refseq: NM_001128918
• Protein Refseq: NP_001122390
• MIM: 602678
• Uniprot ID: P27448
• Chromosome Location: 14q32.3
• Function: ATP binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; protein serine/threonine kinase activity