Recombinant Human MIA2

• Cat.No.: MIA2-30201TH
• Product Overview: Recombinant fragment corresponding to amino acids 20-119 of Human MIA2, 100 amino acids plus a N terminal methionine. Predicted MWt of 11.5 kDa.

Specification

• Description: MIA2 is a secreted cytokine and a member of the MIA/OTOR family. Members of this family which also includes MIA, OTOR, and TANGO share a Src homology-3 (SH3)-like domain. MIA2 is predominantly expressed in hepatocytes.
• Protein length: 100 amino acids
• Molecular Weight: 11.500kDa
• Source: E. coli
• Tissue specificity: Highly expressed in liver and weakly in testis. Expression was higher in patients with severe fibrosis or inflammation and chronic hepatitis.
• Form: Lyophilised:It is recommended to reconstitute the lyophilized MIA2 in sterile ultra pure water not less than 100μg/ml, which can then be further diluted to other aqueous solutions.
• Purity: by SDS-PAGE
• Storage buffer: pH: 7.40Constituents:0.88% Sodium chloride, 98% Phosphate Buffer
• Storage: Please see Notes section
• Sequences of amino acids: MLESTKLLAD LKKCGDLECE ALINRVSAMR DYRGPDCRYL NFTKGEEISV YVKLAGERED LWAGSKGKEF GYFPRDAVQI EEVFISEEIQ MSTKESDFLC L
• Sequence Similarities: Belongs to the MIA/OTOR family.Contains 1 SH3 domain.

Gene Information

• Gene Name: MIA2 melanoma inhibitory activity 2 [ Homo sapiens ]
• Official Symbol: MIA2
• Synonyms: MIA2; melanoma inhibitory activity 2; melanoma inhibitory activity protein 2; FLJ22404
• Gene ID: 117153
• mRNA Refseq: NM_054024
• Protein Refseq: NP_473365
• MIM: 608001
• Uniprot ID: Q96PC5
• Chromosome Location: 14q13.2