"LIFR" Related Products


Recombinant Human Leukemia Inhibitory Factor Receptor Alpha

Cat. No. : LIFR-1663H
Description : LIFR also known as CD118 (Cluster of Differentiation 118), is a subunit of a receptor for leukemia inhibitory factor. LIFR is necessary for the proper development of motor neurons in brainstem nuclei and the spinal cord. LIFR is composed of a heterodimer LIFR alpha and GP130. LIFR alpha is a glycosylated variant of LIFR and is identical with M1 differentiation inducing activity.
Molecular Weight : The predicted molecular weight of Recombinant Human LIF sRα is Mr 89 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 100-110 kDa.
Source : Sf 21 Insect Cells.
State Of Matter : Lyophilized.
Purity : >97% by SDS Page and analyzed by silver stain.
Endotoxin : <0.1 ng per 1 µg as determined by the LAL method.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name : LIFR leukemia inhibitory factor receptor alpha [ Homo sapiens ]
Synonyms : LIFR; leukemia inhibitory factor receptor alpha; SWS; SJS2; STWS; CD118; LIF-R; FLJ98106; FLJ99923; leukemia inhibitory factor receptor; CD118 antigen; LIF receptor
Gene ID : 3977
mRNA Refseq : NM_001127671
Protein Refseq : NP_001121143
MIM : 151443
UniProt ID : P42702
Chromosome Location : 5p13-p12
Pathway : Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway
Function : ciliary neurotrophic factor receptor activity; ciliary neurotrophic factor receptor binding; leukemia inhibitory factor receptor activity; oncostatin-M receptor activity; growth factor binding; receptor activity

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