"MXD1" Related Products

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Recombinant Human MXD1, FLAG-tagged

Cat.No.: MXD1-28856TH
Product Overview: Recombinant full length Human Mad with Flag tag, amino acids 1-221, MW = 26 kDa,
Description: This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Conjugation: FLAG
Source: E. coli
Form: Liquid
Purity: Immunogen affinity purified
Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Contains 1 basic helix-loop-helix (bHLH) domain.
Gene Name: MXD1 MAX dimerization protein 1 [ Homo sapiens ]
Official Symbol: MXD1
Synonyms: MXD1; MAX dimerization protein 1; MAD; max dimerization protein 1; bHLHc58; MAD1;
Gene ID: 4084
mRNA Refseq: NM_001202513
Protein Refseq: NP_001189442
MIM: 600021
Uniprot ID: Q05195
Chromosome Location: 2p13-p12
Pathway: Regulation of Telomerase, organism-specific biosystem; Signaling events mediated by HDAC Class I, organism-specific biosystem;
Function: DNA binding; sequence-specific DNA binding transcription factor activity; transcription cofactor activity; transcription corepressor activity;

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